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The post reports that in a subset analysis of the SUSTAIN trials, adults aged 65 and older achieved mean reductions of 4 to 8 kg over 56 weeks, with relative improvements similar to younger participants

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Time-restricted feeding (TRF), which limits caloric intake to a consistent daily window during the active phase, has shown substantial promise in restoring gut microbial rhythmicity and metabolic coordination (53, 61)