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Additionally, this compound directly inhibits matrix metalloproteinase-2 (MMP-2) , an enzyme crucial for tissue remodeling and cancer metastasis [2]

And the reason for that is several fold

In the acute phase, METH causes an excessive release of dopamine and glutamate, resulting in transient deficits in attention and working memory (Mark et al., 2004)

Pregnancy and breastfeeding call for individualized caution, as with IV nutrients generally

Other deficiencies in B vitamins that may lead to peripheral neuropathy include vitamins B2, B6, and B9

This decline accelerates during caloric restriction, making the deficit state particularly catabolic