MEDVi wins on introductory affordability
Semaglutide medications work by activating the GLP-1 receptor alone, while tirzepatide medications activate both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor, creating what is commonly described as a dual incretin mechanism
For example, if your weekly dose is 6 mg, you would inject 2 mg every two to three days rather than all 6 mg at once
Lower rates of hypoglycaemia in older individuals with type 2 diabetes using insulin degludec versus insulin glargine U100: Results from SWITCH 2
According to Malhotra, Its always been good practice to treat both the sleep apnea and the obesity in the sense that, if somebody has excess weight, rather than just giving them a CPAP, ideally treat the body weight and the sleep apneanot either/or. GLP-1 use doesnt appear to be causing patients to simply abandon their CPAP, either
When these drugs were being developed, researchers observed that rats and mice exposed to high doses of GLP-1 RAs developed an increased incidence of C-cell hyperplasia (an overgrowth of specific thyroid cells) and medullary thyroid tumours
