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A Phase 2 clinical trial published in the New England Journal of Medicine (2023) demonstrated participants receiving retatrutide achieved up to 24.2% mean weight reduction over 48 weeks the highest reduction reported for any investigational compound in its class at that time

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Retatrutides safety profile demonstrated tolerable side effects, predominantly gastrointestinal disturbances, underscoring the need for patient guidance and monitoring

How retatrutide dosing compares to other GLP-1 peptides If you have experience with semaglutide or tirzepatide , you might assume retatrutide dosing follows a similar pattern

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