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It has been suggested that dysregulation of this delicate balance alters cortical activity in the frequency range and that measuring drug-induced changes in cortical activity could serve as a non-invasive objective biomarker for predicting the efficacy of pharmacological interventions (231)

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Dyka, D., Rodze, ., Rodze, M., Pacholak-Klimas, A., Ede, G., Sethi, S., ojko, D., Barto, K., Berry, K., Deptua, A., Grzywacz, Z., Martin, P., Unwin, J., Unwin, D

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Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial