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When VSMCs undergo senescence, they adopt a pro-calcification and osteogenic phenotype (76, 77)

Biochemistry 47, 143156

Urinary glucose and creatinine were measured by colorimetric-enzymatic method using Wako Autokit glucose C2 (Wako) and L-type Wako CRE (Wako), respectively

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Caspases assume a pivotal role in apoptosis, serving as primary executors through the cleavage of cellular proteins, thereby instigating and executing the apoptotic cascade