+5
By simultaneously reducing inflammatory damage, enhancing cellular resilience, and promoting synapse formation, Dihexa addresses multiple pathological processes that contribute to cognitive decline, offering comprehensive neuroprotection rather than targeting a single disease mechanism
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This may also be consistent with impaired mitochondrial biogenesis as described in circulating lymphocytes in chronic inflammatory conditions (45) and in patients with idiopathic ME/CFS (29)
Careful patient stratification and sex-aware trial designs would be essential for evaluating such applications
Note that patients or their legal guardians, researchers, and data analysts will be blinded