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doi: 10.2147/DDDT.S181939 81 YuMQiBXiaoxiangWXuJLiuX

The National Institute for Health and Care Excellence (NICE) guideline NG28 recognises both drug classes as treatment options within the type 2 diabetes management pathway

MC4 receptor engagement leads to appetite suppression and occasional weight loss

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Health and lifestyle information included smoking status (non-smoker vs current smoker), alcohol consumption as units per week, physical activity assessed using the International Physical Activity Questionnaire (IPAQ, expressed in Metabolic Equivalent Total (MET) minutes per week [46], and body mass index (BMI) measured during physical examination