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There are also certain drugs and health conditions that can increase the likelihood of developing a B12 deficiency such as: alcohol abuse, antacid use, smoking, celiac disease, other digestive concerns, pregnancy, a strict vegetarian or vegan diet, and even natural aging

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When disorders of fatty acid -oxidation metabolism and abnormalities of branched-chain amino acid metabolism occur, characteristic alterations of one or more acyl carnitines occur

The influence of UA levels on the progression of oxidative stress and neuroinflammation at different stages of neurodegenerative diseases requires further investigation

Wilson Sonsini Goodrich & Rosati

J Neurochemistry 116(2): 164-176