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Despite this, cyanocobalamin has been increasingly criticised in recent years, due to the following reasons: Toxicity: cyanocobalamin is often claimed to be toxic, as the cyano group form the poison cyanide

Specifically, we proposed to amend 413.20(d)(3) to require hospitals to report the median payer-specific negotiated charge by MS-DRG for MAOs on the Medicare cost report

& Mashek, D

The FDA has flagged concerns about immunogenicity and about peptide-related impurities in unregulated products

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