We obtained the data for this review from PubMed, Scopus, Web of Science, and ClinicalTrials.gov, using the following keywords: obesity, type 2 diabetes, new drug treatment, recent developments, clinical studies, G-protein-coupled receptor, glucagon-like peptide-1 receptor agonists, glucose-dependent insulinotropic polypeptide receptor agonist, glucagon receptor agonist, dual agonist, and triple agonist. 2
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Conversely, high AGE levels exacerbate oxidative stress
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