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Nevertheless, if we fail to incorporate resistance training and sufficient protein intake, this new class of medications could unintentionally contribute to long-term frailty, decreased mobility, and accelerated biological aging (Old et al., 2025)

ROS trigger oxidative stress via various biological processes, such as apoptosis, necrosis, and autophagy, playing critical roles as signaling molecules in the cell death pathway 60

Giufr et al., 2018

Chapter 2.0: Biological Models of Substance Misuse, Pharmacokinetics, and Psychopharmacology Principles Ch

PMID 16893972

It was specifically developed for the dietary management of type 2 diabetes and has a proof-of-concept randomized controlled trial supporting its A1C and glucose-lowering claims