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The cells show features of a confluent monolayer of mature primary hepatocytes with the expected cobblestone morphology covering the plate surface

More serious, albeit infrequent, side effects include pancreatitis (inflammation of the pancreas) and gallbladder problems

In a prospective trial by Mulkens et al

The important thing is that the trajectory is established

We show how cardiolipin, an anionic lipid synthesized in mitochondria and localized to the mitochondrial membrane, may play a central role both in trapping deuterium in the mitochondrial membrane and in inducing protein misfolding to facilitate the formation of deuterium-rich deposits