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Some patients report feeling more alert and energized within hours, while for others, the effects build gradually over the next few days as their body restores B12 balance

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The FDA has issued specific alerts about compounded and grey-market GLP-1 products, particularly during periods when branded-drug shortages caused grey-market supply to expand rapidly

The liver stores B12, and these stores can last a significant time (up to several years for non-deficient individuals), but when they are depleted, it takes consistent input to rebuild and maintain them

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This energy boost can make it easier to stay active and committed to exercise routines