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Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase

2023;46(Suppl1):S1-S4

Human islets from Edmonton were provided by the Clinical Islet Transplant Program and by the Alberta Diabetes Institute Islet Core at the University of Alberta with the assistance of the Human Organ Procurement and Exchange (HOPE) program, Trillium Gift of Life Network (TGLN) and other Canadian organ procurement organizations

Head-to-head data favours the dual agonist for weight

Cipriani A, Barbui C