Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies
Omega-3 fatty acids ingested from foods like sardines, walnuts, seaweed oil, and deep-sea fish provide neuroprotective effects by supporting neuronal development and synaptic activity while reducing inflammation over the gutbrain axis (Latifi et al., 2016)
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These strategies range from established clinical procedures to novel probiotics, natural compounds, and dietary modifications, all converging on the restoration of microbial homeostasis and the reduction of inflammation
Erythropoietin (EPO) can exert neuroprotective effects during the perioperative period, which can be achieved through methods such as reducing cell apoptosis