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Extending treatment to one year, the gap widens: about 4% greater weight loss in non-diabetics on semaglutide, and about 5.5% greater on tirzepatide. Some researchers suggest that behavioral differences such as motivation, adherence and engagement in lifestyle changes might help explain this gap
Many GLP-1 users have noticed that after their four expected doses, theres still medication leftover in their injection pen, which has been dubbed the golden dose by GLP-1 users
The constant cravings and discipline required are mentally taxing
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