Yes, and it is often advisable for long-term users
The charts below show blood glucose levels over a 3 hour period before and after eating a meal
Yang H, Wanner IB, Roper SD, Chaudhari N (1999)
They consist of a HEK293-derived reporter cell line which expresses the specific hormone receptor for GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), or GCG (glucagon), together with a CREB (cAMP-response element binding protein) -inducible SEAP (secreted embryonic alkaline phosphatase) reporter gene
Ultimately, the decision to continue or discontinue GLP-1 therapy should be individualized, considering treatment response, tolerability, patient preferences, cost, and overall health status
Phase 3 trials currently underway will provide more comprehensive long-term safety data