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doi: 10.1038/nm.3761 81 BossartMWagnerMElvertREversAHbschleTKloeckenerTet al

While both clinical and real-world results have shown these medications can improve heart health, new research has found a downside: People who stop taking them quickly lose these improvements and may be at an increased risk of heart attack, stroke, and even death compared with people who stay on them consistently

For semaglutide, this could mean less impact on blood sugar regulation or weight management, potentially delaying your progress

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The result is a brain bathed in inflammatory mediators that amplify cravings, impair impulse control, and degrade the prefrontal cortexs ability to override compulsive urges

Current clinical trials on microbe targeting for CVD therapy are summarized in Table 2 (39)