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The transcription factor cAMP response element modulator (CREM) is highly expressed in male germ cells and regulates the expression of several post-meiotic genes, such as the transition proteins and protamines, and it likely is the key regulator of gene expression during spermatogenesis

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[DOI] [PubMed] [Google Scholar] 196.Jagadeesh S., Suresh B., Murugan V., Suresh S., Salomans G.S., Struys E.A., Jacobs C

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Among those tested, Cur10 demonstrated the strongest binding, exhibiting the lowest IC 50 value of 9.64 M, while Cur07 and Cur06 showed IC 50 values of 19.86 M and 20.79 M, respectively (467)