Rare but serious riskssuch as pancreatitis, gallbladder disease, or certain thyroid tumorsmean that these medications are not suitable for everyone
It depends on how the medication is titrated, monitored, and individualized by providers who treat PCOS specifically, not just obesity
The authors suggest that FFA3 might act to prevent hyperphagia-induced over-secretion of insulin that would cause beta cell exhaustion during dietary-related stress (Priyadarshini et al., 2020)
All weight loss medications have some side effects, but FDA approval means the benefits are considered to outweigh the potential risks
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Their evaluation of the effect of GLP-1 was also aided by their access to RIAs for GLP-1 (Holst 2024)