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GLP-1RAs, such as liraglutide, have been shown to activate brown adipose tissue (BAT) via CNS pathways, promoting thermogenesis and increasing energy expenditure independently of food intake [238240]

In parallel, the reduction in glycemic burden induced by GLP-1 activity creates a metabolic milieu that may restore GIPR sensitivity and functionality

However, because it improves insulin sensitivity, diabetes medications may need to be adjusted

What is a compounded GLP-1 drug

Others maintain their normal eating schedule and let the medication adjust their hunger cues organically

Additionally, an antioxidant-rich diet is essential, with at least five servings of fruits and vegetables daily