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Sleep apnoea reduces the amount of oxygen in the blood, causes frequent awakenings and impairs the quality of sleep
The research literature and clinical experience point toward a few well-established approaches
Khardon et al.(46) described a steroid responsive lymphocytic interstitial pneumonitis in four patients
421 Research, primarily using experimental models of mechanical nerve damage, has explored the mechanisms underlying neuropathic pain, revealing increased excitation and facilitation of pain signals, along with a loss of inhibition in both the PNS and the CNS
Animal models of GHI are available since 1997[31], helping us to better understanding the patho-physiological changes and potentially improved strategies for treating these patients