However, with age, pollution, stress, and UV exposure, the natural production of glutathione declines in the body
DOI: 10.1042/bj0150286 Sekhar RV, McKay SV, Patel SG, et al
chemistry doctoral students Siqing Li and Yingyu Huang
The literature search covered the past 5 years until March 15, 2023
This clearly reduces dark spots, acne marks, tanning, age-related pigmentation, sun-induced pigmentation, and early-stage melasma patches
What Does the Scientific Evidence Say Efficacy & Safety (2025 Overview) When we examine the medical literature (clinical studies, reviews, regulatory data), a clearer and more cautionary picture emerges: A 2015 review of all published studies up to that time concluded that: there is no robust evidence supporting IV glutathione for skin lightening