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Another study reported the opposite finding where baseline serum total ghrelin levels were decreased in early abstinent individuals (72 h) relative to non-abstinent alcohol dependents (Leggio et al., 2012)

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doi:10.1111/andr.12718

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Kudo T, Kanemoto S, Hara H, Morimoto N, Morihara T, Kimura R, Tabira T, Imaizumi K, Takeda M (2008) A molecular chaperone inducer protects neurons from ER stress

In the human trials to date, supplementation was safe and well tolerated, and reported side effects were mild, mainly minor digestive changes