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NICE guidance (NG28) specifies that these agents should generally be considered in people with a BMI 30 kg/m (or lower in certain ethnic groups) and specific problems associated with high weight, or if insulin would have significant occupational implications

A 10mg vial reconstituted with 2mL of bacteriostatic water gives you 5,000mcg per mL

At nearly 30% reduction, many patients are brought into a normal BMI range, an outcome that was previously difficult to achieve without Roux-en-Y gastric bypass or sleeve gastrectomy

Due to high prices and increasing utilization, GLP-1 drugs have quickly become a leading source of retail pharmacy spending, the report states

If youre using a syringe, slowly and steadily push the plunger down until the syringe is empty

They can contribute to lean mass loss if weight loss is rapid and muscle-preserving habits are not in place