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These agents also have direct protective effects on the heart and blood vessels, contributing to a 14% reduction in major adverse cardiovascular events

[DOI] [PubMed] [Google Scholar] 92.Umpierrez G, Pasquel FJ, Duggan E, Galindo RJ

Colesevelam, which requires a much lower quantity of drug because of its high affinity and binding capacity for bile salts, has less of an effect on the absorption of other drugs than other bile acid sequestrants but can still adversely affect the absorption of certain drugs (Table 30) (424)

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This data supports the new findings here now measured across the whole pH range