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Though the recommended doses are not expected to cause adverse effects for the infant, there are no human studies available to assess the risks

There is a lack of long-term safety data in healthy adults

In animal models of PD, mannitol has been shown to inhibit the clumping of alpha-synuclein which is a hallmark of PD pathology

10.1016/j.etap.2013.11.002 292 ShokolenkoI

Research shows injection-site reaction rates typically fall in the 3-10% range

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