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Branded products have faced periodic supply constraints tied to a single manufacturer's capacity against surging demand, while compounded preparations are made on demand by multiple licensed pharmacies across the country

The FDA caught an American company making this exact claim in 2007, ordered it to stop, watched it keep selling anyway, and spent nine years pursuing a case that ended in a felony conviction and a lifetime ban for the owner

These actions result in weight loss, which can be maintained with lifestyle changes due to diet and exercise

The field is moving quickly, and the clinical frameworks around these medications are still maturing

The new data convinces me that we need to think about this differently