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Increasing the oxygen content causes a greater degree of metal complexation, improving effectiveness of heavy metal removal

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However, the saturation effect beyond this level implies that supplementation should be individualized, as excess B12 is unlikely to confer additional benefits

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Efficacy of flapless intentional replantation with enamel matrix derivative in the treatment of hopeless teeth associated with endodontic-periodontal lesions: A 2-year prospective case series