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Free radicals come from normal body processes, but they also increase because of: Poor sleep Stress Alcohol and smoking Illness Medication side effects Poor nutrition Environmental pollutants When oxidative stress rises, your body must work harder to protect and repair itself

In addition to dopamine, norepinephrine, and epinephrine, the VMAT transporters, in particular VMAT2, are responsible for vesicular import of serotonin (5-HT), histamine, and several trace amines such as the tyramines [para-tyramine ( p -tyramine), meta-tyramine ( m -tyramine), 3-methoxytyramine, and N-methyltyramine], -phenylethylamine (-PEA), and thyronamine (3-iodothyronamine)

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Creatinine is excreted by the kidneys and the level of excretion (creatinine clearance rate: CCR) is a measure of renal function