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(2010) 6:e1000756

Catalano PM, Shankar K

Both of these medicines decrease appetite and work best with diet and exercise to help you lose weight and keep the weight off in patients with obesity caused by certain conditions. Is tirzepatide or semaglutide better for weight loss

The result is that many people starting these medications are caught off guard by how they feel in the early weeks, leading some to stop treatment prematurely when the side effects were actually manageable and temporary, and others to push through symptoms that warranted medical attention

There is no consensus on the age at which to start therapy, but there is agreement on starting before the onset of obesity, which often occurs at around 2 years of age (118)

Users who report zero results despite following proper protocols almost invariably trace the failure to questionable product quality