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As GLP-1s can cross the blood-brain barrier and have a direct effect on brain function, it is important to examine their impact on mental health, especially in patients with mental illness. Researchers conducted a systematic review of studies assessing the impact of GLP-1s on mental health and metabolic outcomes in people with and without a mental illness between 2010 and August 2024

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These changes connect to enhanced metabolic indicators like decreased insulin resistance and reduced hepatosteatosis