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(177)Lu-DOTATATE for the treatment of gastroenteropancreatic neuroendocrine tumors

The qualification of biomarkers for drug development is not only a scientific hurdle but also a regulatory one

The peptide backbone is stabilized by disulfide bonds and secondary structure folds that maintain bioactivity

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Intriguingly, a Western diet high in PUFAs can induce intestinal inflammation in mice lacking one allele of GPX4 in IECs, which implies that dietary PUFAs may be a trigger of GPX4-restricted mucosal inflammation phenocopying aspects of human CD (143)

Bone marrow mesenchymal stem cell-derived exosomes miR-367-3p, in Erastin-induced BV2 cells, targets the binding enhancer of zeste homolog 2 (EZH2), inhibiting its expression