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The excretion and accumulation of these conjugates are strongly linked to renal dysfunction and end-stage renal failure (Ahmed et al., 2017)

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In all, 13 out of the 35 predicted common essential genes were shown to be involved in the cholesterol biosynthesis pathway, 1 in cardiolipin synthesis, 2 in glycerophospholipids, 5 in sphingolipid metabolism, 6 in de novo synthesis of nucleotides (CMPK1, TXNRD1, CAD, DHODH, UMPS, GUK1), and 5 genes in de novo synthesis of fatty acids (ACACA, LCAT, LIPA, FASN HSD17B4), respectively (Supplementary Table 2)

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Molecular formula: C38H49N9O5