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Genetic variations linked to weight loss, side effects from GLP-1 drugs (Reuters) - Weight-loss responses to GLP-1 obesity drugs, and risks of side effects, may be linked to genetic variants, according to a study conducted by DNA-testing service 23AndMe

10.1016/j.amjmed.2020.03.030 Am

A., Bartlett S., He L., Nielsen C

Peripherally circulating GLP-1 (143) and some GLP-1RAs, such as liraglutide and semaglutide (145), can readily access the CVOs, including the subfornical organ and the area postrema, which express GLP-1R and have close neuroanatomical connections with hypothalamus involved in forage and satiety control

PMID 31157404

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