Spaide RF, Gemmy Cheung CM, Matsumoto H, Kishi S, Boon CJF, van Dijk EHC, et al
Diabetic nephropathy (DN) is the main secondary complication of diabetes mellitus (DM)
Combining cagrilintide peptide with semaglutide weight loss therapy may increase these effects initially, but tolerability usually improves over time
Patients who took a high dose of tirzepatide lost 22.5% of their body weight on average, or 52 pounds, better than any medication currently on the market
Cardiovascular and Metabolic Improvements Beyond weight loss, semaglutide has been shown to reduce blood pressure, improve cholesterol profiles, and decrease markers of systemic inflammation all of which contribute to a lower risk of heart disease and metabolic syndrome
Methods Study Design This was an interventional, multicentre, randomised, open-label, three-group, full replicate crossover study