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Inhibition of Melanin Production Melanin is the pigment that gives our skin its color

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from Consejeria de Salud (PI-0397-2017) and Consejeria of Economa, Conocimiento, Empresas y Universidad of the Junta de Andalucia (P18-RT-2501)

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The stable gastric pentadecapeptide BPC 157, an original cytoprotective antiulcer peptide that is used in ulcerative colitis and recently in a multiple sclerosis trial and that has an LD1 that has not been achieved [1,2,3,4,5,6,7,8,9,10,11], is known to have pleiotropic beneficial effects [1,2,3,4,5,6,7,8,9,10,11] and to interact with several molecular pathways [2, 27,28,29,30,31,32]

To calculate the slow accumulation of contrast agent, a linear fit was applied to min 622 of the concentration curve of each voxel with normalization to the venous input function, which is the leakage rate of the superior sagittal sinus