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BRD4 is an epigenetic reader that regulates gene expression by forming a complex with the positive transcription elongation factor b (P-TEFb), promoting RNA polymerase II (Pol II), a mediator of DNA-dependent RNA synthesis (Jung et al., 2014)

[26] found that the concentration of Fe 2+ increased in ATDC5 cells after stimulation with IL1

Vitamin D deserves separate mention because fat loss releases stored vitamin D from adipose tissue, temporarily increasing blood levels, but long-term reduced fat intake can lead to deficiency