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The prediction may be based on theoretical considerations of chemical structure, possibly on in vitro experimental results, on in vivo animal data, and on prior observations in humans

This includes individuals with prediabetes (HbA1c 5.76.4%, fasting glucose 100125 mg/dL, or 2-hour glucose 140199 mg/dL on oral glucose tolerance testing) who have elevated BMI and have not achieved adequate results with lifestyle interventions

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[DOI] [PubMed] [Google Scholar] 138.Agnihothri R.V., Courville A.B., Linderman J.D., Smith S., Brychta R., Remaley A., Chen K.Y., Simchowitz L., Celi F.S

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