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Previous study demonstrated that acupuncture is better than metformin at improving glucose metabolism, but it is less effective at increasing insulin sensitivity in women with IR and PCOS compared to metformin [144]

However, the results showed that in addition to the cardiovascular safety of GLP-1 receptor agonists, some drugs in the class can have influence on major adverse cardiovascular event (MACE) reduction compared to placebo (37)

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2017), and three-dimensional (3D) (Li et al

infusions in humans

FIGURE 2 5.2 Clinical application of intranasally delivered drugs Although IN delivery of iron chelators remains in the early preclinical stages and has not yet entered clinical trials, the broader field of IN route has gained increasing attention over the past decade, as evidenced by a notable rise in related clinical studies