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We cannot know the true response rate

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The good news is there are no [known] contraindications unless you are allergic to some of the components to taking collagen supplementation and few side effects, says Manning

Berberine is usually taken as an oral capsule several times a day

Side Effects Some patients may experience mild side effects such as nausea, diarrhea, or constipation

Early clinical research has suggested it may support significant reductions in fat mass, which is why it has gained strong attention in the field of obesity and metabolic disorder research