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Consistency matters for maintaining steady blood levels

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10.9734/BJMMR/2016/24910

The isoelectric point of semaglutide sits around pH 5.4, and degradation accelerates significantly between pH 4.5 and 5.5, which means that any formulation changes caused by temperature exposure can compound the problem by shifting the solution toward less stable conditions

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What baseline testing should we require before starting patients on GLP-1 medications