Udell JA, Bhatt DL, Braunwald E, Cavender MA, Mosenzon O, Steg PG, Davidson JA, Nicolau JC, Corbalan R, Hirshberg B, Frederich R, Im K, Umez-Eronini AA, He P, McGuire DK, Leiter LA, Raz I, Scirica BM, SAVOR-TIMI 53 Steering Committee and Investigators
Body weight and baseline IGF-1 levels inform dosing decisions
As both came off the shortage list, the legal basis for large-scale compounding under the shortage exception collapsed
2021;2(6):e31726
Environmental enrichment prevents stress-induced epigenetic changes in the expression of glucocorticoid receptor and corticotrophin releasing hormone in the central nucleus of the amygdala to inhibit visceral hypersensitivity
This warning is based on animal studies showing an increased incidence of thyroid tumors in rodents exposed to GLP-1 receptor agonists