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Since 2020, prescriptions for GLP-1 drugs have more than tripled, researchers said in background notes

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The inverse variance weighted (IVW) model was recruited as the primary two-sample MR analysis approach, followed by sensitivity analyses such as the heterogeneity test, horizontal pleiotropy test, leave-one-out analysis, and linkage disequilibrium score (LDSC) regression

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The suppression of K63-ubiquitination of KEAP1 is mediated by OTU deubiquitinase 1 (OTUD1), which may inhibit ROS-induced oxeiptosis in kidney cancer cells [161]