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Patutina OA, Gaponova Miroshnichenko SK, Senkova AV et al (2020) Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency

This kind of approach akin to an antibiotic but ultra-narrow in spectrum could be used for other microbial pathways too

Camargo et al., 2019)

"I see it as very risky," says Paul Knoepfler, a cell and molecular biologist at the University of California, Davis who has tracked the upsurge in demand for these peptides

In the body, it is transformed into both bioactive coenzyme forms: methylcobalamin and adenosylcobalamin

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