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J Alzheimers Dis 2015;44:705-20

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Ipamorelin Selective GHS-R Agonist Pentapeptide Compound Name: Ipamorelin Classification: Research Peptide Growth Hormone Secretagogue Receptor (GHS-R) Agonist Description: Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH) known for its highly selective interaction with the growth hormone secretagogue receptor (GHS-R), a subtype of the ghrelin receptor family

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Given the peptide's short plasma half-life (~0.51 hour), daily dosing maintains more consistent exposure to the peptide's gene-expression-modulating effects