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11.5 Who Should Be Monitored More Closely Monitoring becomes more relevant when: Weight loss exceeds 1520% Appetite suppression leads to persistent under-eating GI symptoms persist Pre-existing marginal status exists Combination therapy (e.g., metformin) is used Older adults are treated Oversight should be proportional to risk

Why GLP-1 Weight Loss Shows Up First in the Face Facial changes during weight loss come from a combination of rapid fat reduction, age-related collagen shifts, hormonal changes, and the skins ability, or inability, to adjust

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The net result is a drug that doesnt just help people eat less it changes how their metabolism runs

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It also acts as a cryoprotectant during the freeze-drying process that many compounded formulations undergo, protecting the peptide structure from freezing-related damage