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doi:10.1155/2018/3763565 Eskes SA, Endert E, Fliers E, et al
Copper peptides support barrier function rather than disrupting it, making them potentially gentler than many other active ingredients
Ruggeri, S
The copper uglies happen because GHK-Cu actively signals skin regeneration, which can temporarily surface underlying issues like clogged pores, low-grade inflammation, or trapped sebum
Simultaneous use of NSAIDs with corticosteroids, anticoagulants, aspirin, platelet inhibitors, and serotonin re-uptake inhibitors can increase gastrointestinal toxicity up to 15-fold
doi: 10.1016/j.freeradbiomed.2009.07.023 34 SainiRSinghS
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