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Published 2018

While the liver was previously thought to be the main target of metformins glucose-lowering effects, recent evidence suggests that other parts of the body, such as the gastrointestinal tract, also play a role in its overall clinical advantages

GLP-1s are heat-sensitive

The six-month data showing average HbA1c reductions of up to 2.4 percentage points and an average weight reduction up to 11.3 kg (12.7 percent) were presented today at the 54 th Annual Meeting of the European Association for the Study of Diabetes in Berlin and simultaneously published in The Lancet

This means that the drug helps increase insulin levels only when blood sugar is high, reducing the risk of hypoglycemia, a common issue with some diabetes treatments

*-OHdG is widely used as a marker of oxidative stress and other degenerative conditions